Shiitake Extract 30% Polysaccharides: A Natural Immune Enhancer
Shiitake Extract 30% Polysaccharides: A Natural Immune Enhancer
In the field of natural active ingredients, Lentinula edodes has always occupied an important position due to its long history of edible and medicinal use and rich bioactive substances. Among them, lentinan, as the core active component, has been widely concerned by the global scientific research and industrial communities. Our shiitake extract with 30% polysaccharides maximizes the health value of shiitake mushrooms through precise extraction and strict quality control, providing high-quality natural raw material support for medicine, health products, functional foods and other fields.
Lentinan is a type of highly branched polysaccharide with β-1,3-glucan as the main chain and β-1,6 glycosidic bonds as the side chains. Its standardized content of 30% ensures the stable efficacy of the product. As a classic host immune enhancer, it can specifically bind to the Dectin-1 receptor on the surface of macrophages and NK cells, activate the phagocytic capacity of immune cells, and promote the differentiation of T cells into effector T cells, enhancing the body’s ability to recognize and eliminate viruses and cancer cells. In adjuvant cancer treatment, when used in combination with radiotherapy and chemotherapy, it can significantly reduce treatment side effects and improve patients’ quality of life. Clinical studies have shown that the remission rate of the combined group is 15%-20% higher than that of the single radiotherapy and chemotherapy group. In addition, its antiviral properties have been verified in the treatment of chronic hepatitis B, which can improve patients’ clinical symptoms and promote the recovery of liver function indicators to normal.
In addition to the core functions of immune regulation and anti-tumor, shiitake extract 30% polysaccharides also have multiple health benefits. It can scavenge superoxide anion free radicals and hydroxyl free radicals in the body, reduce oxidative stress damage to cells, and exert antioxidant and anti-aging effects; in terms of metabolic regulation, it can improve insulin sensitivity, reduce blood cholesterol and triglyceride levels, and has positive significance for maintaining cardiovascular health and blood sugar stability. With the characteristics of good water solubility and high bioavailability, this product can be flexibly applied to various dosage forms such as capsules, tablets, oral liquids, and functional drinks, meeting the development needs of different scenarios.
Our shiitake extract 30% polysaccharides are made from high-quality shiitake mushroom fruiting bodies through traditional hot water extraction combined with modern refining technology. The whole process follows international standards such as ISO and HACCP to ensure high purity, low impurities and good safety of the product. Each batch of products undergoes strict multiple tests: the core polysaccharide content is accurately determined by HPLC to ensure a standardized range of 30.0%±1.5%, among which the content of β-glucan accounts for no less than 70% of the total polysaccharides, the weight-average molecular weight is stably around 1.8×10⁶Da, and the molecular weight distribution is concentrated (polydispersity index ≤1.01); purity testing shows that the ash content of the product is ≤5.0%, loss on drying is ≤7.0%, and no starch dextrin auxiliary materials are added; safety indicators are all superior to national standards, the total content of heavy metals (lead, arsenic, mercury) is ≤10ppm, and the microbial limit meets the requirements of food-grade raw materials (total bacterial count ≤1000CFU/g, mold and yeast ≤100CFU/g, no pathogenic bacteria detected), providing customers with stable and reliable raw material guarantee.
Relevant authoritative literature support:
1. Meng Zhang, et al. Mushroom polysaccharide lentinan for treating different types of cancers: A review of 12 years clinical studies in China. Prog Mol Biol Transl Sci. 2019. doi: 10.1016/bs.pmbts.2019.02.013.
2. Special Functional Plant Polysaccharides. 360doc Personal Library. 2025-07-14.
3. Efficacy and Function of Lentinan. Youlai Doctor. 2025-04-15.
